Alex Michaelides was born in Cyprus in 1977 to a Greek Cypriot father and an English mother. He studied English literature at Trinity College, Cambridge, and then screenwriting at the American Film Institute in Los Angeles. He also trained in psychotherapy and worked for two years in a secure unit for young people, which he drew on for his first novel.
His early career was in film. He wrote the screenplay for The Devil You Know (2013) and co-wrote The Brits Are Coming (2018).
The Silent Patient (2019) is a psychological thriller about Alicia Berenson, a painter who shoots her husband and then never speaks again, and Theo Faber, the psychotherapist who sets out to make her talk. It entered The New York Times bestseller list at number one and has sold millions of copies. Some reviewers found its final twist strained. His later novels, The Maidens (2021) and The Fury (2024), are also mysteries. He lives in London.